37 Results were found on Technologies

Leading Researchers:

Guided Regeneration Gel: A novel biocompatible hydrogel for peripheral nerve reconstruction and wound healing

The Technology Guided regeneration gel (GRG) is a novel biocompatible, biodegradable hydrogel for peripheral nerve reconstruction, cell therapy and wound healing. Similar to the extracellular matrix (ECM), GRG is transparent, highly viscous,... Read More >

Oncomir expression directed targeted chemotherapy

The InventionMicroRNAs (miRNAs) are an abundant class of short endogenous noncoding RNAs that act as post-transcriptional regulators of gene expression by base-pairing with their target mRNAs. To date, several hundred miRNAs have been described in... Read More >

Leading Researchers:

Novel ALS biomarkers:Towards diagnostics and potential therapy

The TechnologyNovel ALS biomarkers, differentially expressed in blood and bone marrow samples from ALS patients have been identified. These are Cytoplasmic FMR Interacting Protein 2 (CyFIP2) and Retinoblastoma (Rb) Binding Protein 9 (RbBP9)... Read More >

Leading Researchers:

ZZ-PE38: a universal technology for immunotherapy

The TechnologyA novel fusion protein capable of binding to any internalizing IgG, thus forming a specific and potent immunotoxin, has been developed. The antibody-toxin conjugate is formed through an immuno-complex and may be further stabilized by... Read More >

Leading Researchers:

Silencing of Mortalin with siRNA as adjuvant for cancer immunotherapy

TechnologyA novel mode of treatment by inhibition of mortalin or mortalin synthesis as an adjuvant to antibodybased immunotherapy.Novel siRNA was designed as blocker of Mortalin expression. The anti-mortalin siRNA binds specifically to mortalin... Read More >

Targeting bone neoplasms and other cancers with novel combined anticancer and anti-angiogenic polymer therapeutics

Anti-cancer NanoTherapyUtilizing unique nano-technology to develop targeted combination nanomedicines that were shown to be synergistic, effective and safe for treating cancer TechnologyWe have developed a new platform technology for the... Read More >

Leading Researchers:

Immunotherapy for the prevention and treatment of osseous metastasis

Technology SVEP1 is a novel cell adhesion protein. Its expression is primarily associated with bone cells but is also expressed by breast carcinoma cells. Anti-SVEP1 antibodies block cell adhesion in in vitro matrix. Prevention... Read More >

Leading Researchers:

Improved Calcitonin-based Therapeutics

TechnologyThe aggregation site on human calcitonin has been identified, paving the way for development of specific inhibitors of calcitonin amyloid fibril formation. Such inhibitors will enable development of improved calcitonin therapeutics as... Read More >

Leading Researchers:

Novel markers for the identification and isolation of stem and progenitor cells

TechnologyA series of novel markers: (1) chromatin remodeling protein factor termed (CHD9/CReMM), (2) A cell adhesion protein termed (SVEP1), (3) A kinesin protein termed (MS-KIF18A), (4) RNA processing factor (SRRF/hNRNP-L) have been developed as... Read More >

Leading Researchers:

BBS (? secretase Blocking Site) Ab -A novel target for Alzheimer's and ALS immunotherapy

THE TECHNOLOGYBBS is a monoclonal antibody that binds specifically and blocks beta-secretase (BACE1) cleavage site on its substrate, APP. BBS inhibits Ab production, a hall-mark of AD and other neurodegenerative diseases such as ALS.The... Read More >