37 Results were found on Technologies

Leading Researchers:

Cell Therapy for Diabetes: Expansion and re-differentiation of adult human pancreatic islet cells for transplantation

The insulin-producing pancreatic islet β cells are destroyed in type 1 diabetes (T1D) by autoimmunity, and malfunction in type 2 diabetes (T2D), which together afflict >5% of world population. Restoration of a functional β-cell mass by... Read More >

Leading Researchers:

Novel oral formulation of Insulin

The TechnologyGagomers are novel particles (neither liposomes nor microspheres/ nanospheres) composed of hyaluronan shell which is crossed linked to phospholipids and can be generated either as micro or nano particles. The research team at Tel Aviv... Read More >

Leading Researchers:

Novel Derivatives of Valproic Acid and Acyclovir as Selective Anti-Cancer Agents

TechnologyHistone deacetylase inhibitors (HDACis) have emerged as a powerful new class of anticancer agents acting through the regulation of histone and other proteins acetylation. However, the current FDAapproved HDACis SAHA and FK228 used for... Read More >

Leading Researchers:

Targeting the voltage sensor of Kv7.2 and TRPV1 cation channels: Novel treatment for neuropathic pain

TechnologyWe designed unique ligands targeting the voltage sensor domain (VSD) of two voltage-gated cation channels (VGCC), Kv7.2 and TRPV1 channels. These drugs simultaneously function as openers of Kv7.2 and blockers of TRPV1. They act in vitro... Read More >

Leading Researchers:

GSK-3 Peptide Inhibitors for the Treatment of CNS Related Disorders

Technology Novel Glycogen synthase kinase 3 (GSK-3) inhibitors were developed. These inhibitors are substrate competitors that interact specifically with the GSK-3 substrate binding site. The strategy is based on exploiting the unique... Read More >

Leading Researchers:

IAPP Oligomers as a Target for Type 2 Diabetes Novel Immunotherapy

TechnologyStabilized human IAPP (hIAPP) oligomers were used for the development of active immunization of type 2 diabetes. This promising novel approach for the treatment of type 2 diabetes is doable due to the establishment of a new protocol for... Read More >

Leading Researchers:

Low energy laser bio-stimulation of bone marrow stem cells for the treatment of myocardial infarction

The Device rLLLT is a remote (non-invasive) Low Level Laser Therapy to the tibia of AMI patients. rLLLT mobilizes autologous bone marrow stem cells into the blood stream, where they home to the ischemic organ, induce paracrine secretion of... Read More >

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Mouse model of progressive multiple sclerosis

The Technology Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by damage to the neuronal myelin sheath, which results in different levels of muscle paralysis that can lead to neuronal death. In... Read More >

Drug Treatments Targeting Glioma Microenvironment: CD38 inhibitor as a Potential Therapeutic Approach for Glioma Treatment

OUTLINE CD38 is an ectoenzyme that generates Ca2+ mobilizing agents and regulates nicotinamide adenine dinucleotide (NAD) levels. We showed that via its enzymatic activity CD38 promotes the supporting role of tumor microenvironment (TME) cells... Read More >

Leading Researchers:

Quantitative confluency measurement of culture growth

The invention is an image processing method of light microscopy images for the purpose of quantifying density of cells in cultures . A grayscale image of a cell culture is digitally captured using a light microscope and a CCD camera... Read More >