38 Results were found on Technologies

Anti IL-13R alpha 1 antibody for the treatment of asthma and other diseases such as eosoniphilia and atopic dermatitis

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Leading Researchers:

Targeting DHODH to treat epilepsy and MCI

Our work proposes a specific method to treat epilepsy by reducing activity set-points inhippocampal circuits. In particular, we identified mitochondrial dihydroorotate dehydrogenase (DHODH) enzyme as a central regulator of firing set-points in... Read More >

Leading Researchers:

SK4 K+ channel blockers: a new treatment for cardiac arrhythmias

We discovered a previously unidentified target in the heart, namely the SK4 calcium-activated K+ channels, which are functionally expressed in pacemaker cells and atrial cardiomyocytes. They are crucial for proper cardiac rhythm and represent a... Read More >

Leading Researchers:

Immunotherapy using CAR-T cells targeting aberrant glycosylation in cancers

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Leading Researchers:

Therapeutic vaccine for the treatment of cancer

An active cancer vaccine strategy targeting tumor-associated carbohydrate antigens expressed on tumor cells using biomimetic glyconanoparticles generated from unique red blood cells. The resulting sustained immune response inhibits tumor... Read More >

Leading Researchers:

Monoclonal Antibodies Against Novel Targets in Antibiotic Resistance Bacteria

We developed a monoclonal antibody (mAb-B7) that has high potential to become a potent drug that would be used in preventing and treating infections caused by antibiotic-resistant pathogens such as EPEC, EHEC and others. UNMET... Read More >

Leading Researchers:

Coronavirus Epitope-Based Vaccine for MERS and other infectious diseases

Vaccines are most definitely the most effective medical intervention employed towards the improvement of Public Health. Currently vaccine modalities fall into 4 categories: killed, attenuated, subunit and DNA. All of these elicit a... Read More >

An antibody against Semaphorin 3A for treatment of degeneration diseases of the optic nerve

Glaucoma is a term which covers different pathological conditions leading to neuropathy, degeneration of the vulnerable optic nerve axons and cell bodies (Retinal Ganglion Cells = RGC). The most common glaucoma is associated with high intraocular... Read More >