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Novel markers for the identification and isolation of stem and progenitor cells

Technology
A series of novel markers: (1) chromatin remodeling protein factor termed (CHD9/CReMM), (2) A cell adhesion protein termed (SVEP1), (3) A kinesin protein termed (MS-KIF18A), (4) RNA processing factor (SRRF/hNRNP-L) have been developed as novel markers for the identification and isolation of stem and progenitor cell.

Potential Applications

  • Identification of stem cells from skeletal muscle, mesenchymal cells and adipose derived stem cells
  • Isolation and enrichment of specific sub populations of stem cells and progenitors cells
  • Modulation of expression for controlled differentiation of MSCs
  • QC for cell differentiation

Stage of development
Antibodies have been raised to monitor protein expression in in vitro and in vivo studies

Patents
7,829,296; 7,919,602
US pending