1 Results were found on Technologies
Sub Category Name
Targeting Human Brain Cells With Adeno-Associated Virus (AAV) for a Prospective Therapeutic Approach
The AAV therapeutic approach for various central nervous system (CNS) illnesses has been rapidly growing. Unfortunately, existing present technologies utilize AAV administration that is injected locally into the brain. This process requires a high level of expertise and is not applicable in more diffused brain targets like cortex and stiratum. Systemic administration of AAV vectors through […] Read More >
Prof. Barak Segev
Dr. Barak’s research focuses on the psychobiology and neurobiology of alcoholism and drug addiction. In particular, he is interested in the molecular and neuronal mechanisms that underlie learning and memory processes in alcohol addiction. In addition, Dr. Barak is interested in the pathophysiology of schizophrenia, with focus on cognitive impairments in this disorder. See lab […] Read More >
Prof. Ben-Baruch Adit
Breast cancer is a leading cause of death for women in the Western world. The battle against breast cancer has been challenged by the fact that, generally, each component is studied meticulously, but singly. Too little attention is paid to the interactions between the tumor cells and their intimate microenvironment, consisting of various cells and […] Read More >
Dr. Burstein David
Dr. Burstein is a faculty member in The Shmunis School of Biomedicine and Cancer Research in the Life Science Faculty at Tel Aviv University. His research focuses on CRISPR-Cas systems, secretion systems of pathogens, and the discovery of novel antibiotic resistance genes to better understand fundamental interaction mechanisms within microbial communities and to promote their […] Read More >
Prof. Frenkel Dan
Research topic: The research in our laboratory is focused on the investigation of glial cell and to clarify their role in neurological diseases. We suggest that targeting glia activation in different pathological scenarios may allow us to define common pathways to further understand the role of glia in neuroprotection . We are using three models: 1) […] Read More >
Prof. Gabet Yankel
Genetics: Our laboratory focuses on the genetic and hormonal regulation of bone remodeling, microarchitecture and strength. These traits have a high degree of heritability, and one aspect of our research is to characterize new genetic determinants of bone remodeling as well as elucidate the mechanism of action of selected genes. Our GWAS confirmed the role of […] Read More >
Dr. Gil-Ad Irit
Dr. Gothilf Yoav
Research Activity The Circadian Clock system All organisms demonstrate a wide variety of behavioral and physiological daily rhythms that are driven by an evolutionary conserved endogenous circadian clock mechanism. Maintenance of circadian rhythms is crucial for the physical and mental wellbeing, and disruption of the rhythms increases susceptibility to diseases and psychiatric disorders. Utilizing the […] Read More >
Dr. Harlev Mickey
The Tel-Aviv University (TAU) holds several regular and SPF (Specific Pathogen Free) animal care facilities, providing state-of-the-art non-clinical and pre-clinical laboratory research services. We can perform multi-level studies, using a large variety of animals and supply veterinarian services, to our TAU researchers and to external companies and institutes. We provide a continuum of complete tailor-made […] Read More >
Prof. Joel Daphna
Prof. Joel studied the involvement of basal ganglia-thalamocortical circuits in normal and abnormal behavior, using mainly animal models of psychopathology. More recently Prof. Joel has expanded her work to research questions related to brain, sex and gender. Ongoing studies attempt to characterize the relations between sex and brain structure and function. Other studies focus on […] Read More >
Dr. Leikin-Frenkel Alicia
Reproduction in Animal Models and in Humans
Our research focuses on Reproductive Physiology in animal models and in humans. The current research directions investigated in the laboratory are: The role of Fyn kinase, member of the Src family kinases, during meiosis and early events of oocyte activation, as well as in cancer cells (Figure-left panel). Fertility preservation – the signaling pathway leading […] Read More >
The Myers Neuro-Behavioral Core Facility
Unit description:The Myers Neuro-Behavioral Core Facility provides researchers with state-of-the-art technology for performing neuro-behavioral tests in mice. Services: The Core Facility provides expertise in design, implementation, and analysis of behavioral experiments. The Core Facility includes five behavior rooms, which can operate simultaneously, and two animal maintenance rooms with IVC cages operating on a reversed light […] Read More >
Animal models of Addiction and Psychopathologies
Our main focus is on the psychological and neurobiological mechanisms that underlie psychiatric disorders, and in particular addiction We are using rodent models of addiction, anxiety, learning and memory. We focus on behavioral models relevant to different stages of addiction (craving, drug reward, intoxication, sensitization, tolerance, excessive alcohol consumption, withdrawal symptoms, relapse). We are looking […] Read More >
MULTI SENSOR – Multi Modal Recording System for Behavioral Tracking
It is clear today that brain activity of a restrained (or sedated) animal is completely different from that of a freely behaving animal.That is why neuroscientists are seeking to find ways to study animals freely behaving on their natural grounds.TAU’s interdisciplinary research has led to the development of the MULTI SENSOR – Multi Modal Recording […] Read More >
analysis of mineralized tissues using microCT
The general purpose of my research is to describe the genetic and endocrine regulation of bone metabolism. To this end, we developed expertise in most aspects of bone research, from in vivo models, imaging of bone microarchitecture, in vitro cell cultures and molecular biology. Main Research Topics Regulation of bone metabolism by sex steroids Role […] Read More >
The Cohen Rosenthal Diabetic Hypertensive Rat (CRDH) model
The construction of the Cohen Rosenthal Diabetic Hypertensive Rat (CRDH) model was initiated nearly a decade ago by cross-breeding between the Cohen Diabetic rat (CDR) and the SHR. The CDR is a rodent model that expresses the following phenotypes: when fed regular diet, it is non-diabetic; when fed a diabetogenic diet, it invariably develops diabetes […] Read More >
Laboratory of Immunological and Inflammatory Modules in Malignancy
Research focusProf. Ben-Baruch is an immunologist who investigates the roles of immune and inflammatory elements in physiological and pathological conditions, with major emphasis on malignancy. The studies in her laboratory determine the complex regulatory networks established between chemokines and cytokines of the tumor microenvironment, intrinsic oncogenic modifications in tumor cells, and stroma cells. The research […] Read More >
Lab of Cancer Angiogenesis and Nanomedicine
Selective therapy remains a key issue for successful treatment in cancer therapy. Prolonged administration of effective concentrations of chemotherapeutic or anti-angiogenic agents is usually not possible because of dose-limiting systemic toxicities involving non-malignant tissues. Therefore, a constant effort has been the development of new drug delivery systems that mediate drug release selectively at the tumor […] Read More >
Zebra fish model
The circadian clock system: from molecular mechanisms to physiology and behavior Research methods: Molecular genetics in whole animal, the zebrafsh; Transgenesis and gene manipulation; Behavior (mainly locomotor activity rhythms). Available Research Services Analysis of circadian rhythms of locomotor activity of wild type zebrafish and of mutants with advanced (short) or delayed (long) circadian […] Read More >
Lipid Solutions and Animal Model
SERVICES“ Lipid Solutions” Prof. Alicia Leikin-Frenkel “Lipid Solutions” covering:1. Expert support for questions on: lipid metabolism, isolation, identification and quantitation of lipids in different species and different matrixes.2. Guidance to discover the pathway to physiological and biochemical implications following overexpressed or suppressed gene linked to lipids.3. Counseling to analyze lipids in:• Simple molecules: fatty acids: Saturated, Monounsaturated n7, n9, Polyunsaturated: […] Read More >
