SK4 K+ channel blockers: a new treatment for cardiac atrial fibrillation
We discovered a previously unidentified target in the heart, namely the SK4 calcium-activated K+ channels, which are functionally expressed in pacemaker cells as well as in atrial and ventricular cardiomyocytes. They are crucial for proper cardiac function and represent a completely new therapeutic target for the treatment of cardiac arrhythmias. SK4 channel blockers successfully prevented […] Read More >
Novel Immuno-Metabolism Pathways to Combat Obesity and Insulin Resistance
Nutritional unbalance develops the obesity led to diabetes and accompanied by insulin resistance is being the epidemics of the 21st century. Inflammation of adipose tissue serves one notable pathway that is driving the development of dysfunctional metabolic state, leading to hyperglycaemia and other pathophysiology complications. Within the adipose tissue, a pivotal role in modulating interactions […] Read More >
Prof. Attali Bernard
Reaching an understanding in molecular terms of the mechanisms by which changes in membrane potential regulate cellular events is the main concern of our research. We focus our interest on potassium channels because they play crucial roles in many cellular functions such as shaping cardiac and neuronal action potentials, tuning neuronal firing patterns, synaptic integration […] Read More >
Prof. BARNEA Ofer
Patient specific models: Assessment of fetal cardiovascular development Optimization Propofol administration during anesthesia Optimization of fluid resuscitation Assessment of cerebral blood flow autoregulation Multiscale models of physiological systems 3D fiber based model of the contracting heart Oxygen transfer to tissue Biomedical measurements and instrumentation Optimally controlled fluid administration system Detection of bubbles in blood to […] Read More >
Prof. Benayahu Dafna
Nanomedicine is medical treatment at the level of single molecules or molecular assemblies that provide structure, control, signaling, homeostasis, and motility in cells, i.e., at the “nano” scale of about 100 mm or less. There have been many scientific and technological advances in both physical and biological sciences over the past several years that make nano medicine […] Read More >
Microfluidics-based tissue engineering. Recreating stem cell niches, microfluidics bioreactors for tissue engineering. Nanotechnological strategies for engineering thick cardiac tissue. Engineering a 3D neuronal network for spinal cord and brain regeneration. Fabrication of Nanoelectronics/engineered tissue hybrids. Developing smart delivery systems that recruit stem cells to defected organs. Email: tdvir@tauex.tau.ac.il Phone: 03-6406514 Another phone: 03-6408604 Website: https://dvirlab.wixsite.com/dv… Office: […] Read More >
Prof. Einav Shmuel
Research Interests: Flow in biological systems; cardiac blood flow; Blood flow in obstructed arteries and in bypasses; blood flow through artificial heart valves; Cardiac-assist devices; magnetic resonance imaging of blood flow Read More >
Research Isolation of bio active natural compounds, mainly , anti bacterial , anti viral and/or cytotoxic compounds from plants and mainly marine organisms ( soft corals, sponges and tunicates ). The compounds belong to the various bio-synthetic groups , namely , terpenoids , polyketides and nitrogen containing compounds ( alkaloids ? ) . The structure […] Read More >
Prof. Jonathan Leor
Professor Leor received an M.D. degree from Tel-Aviv University, continued training in cardiovascular medicine at the Sheba Medical Center, and completed his post doctorate training at the University of Southern California, Los Angeles, under Robert A. Kloner, M.D., Ph.D. Today, his laboratory’s research focuses on infarct repair and the heart’s lack of intrinsic regenerative ability. […] Read More >
Prof. Margalit Rimona
Research Interests 1. Micro- and nano-particulate drug delivery technologies for topical, regional and systemic applications: Our efforts in the drug delivery arena focus on two drug delivery technologies, one veteran and one novel, that are inventions of our group. These technologies each yield, micro and nano sized particles that are composed of biomaterials with particular […] Read More >
Prof. Galit Yovel is the Head of the SCAN@TAU Center SCAN@TAU Center The Strauss Computational Neuroimaging Center George S. Wise Faculty of Life Sciences https://mri.tau.ac.il/about The center’s services SCAN@TAU center is a new MRI multidisciplinary research center at Tel Aviv University that offers cutting edge MR technologies and innovative, high-resolution imaging methods. The […] Read More >
Lab Description Using the powerful combination of molecular biology, biophysics, biochemistry and electrophysiology. our research aims at elucidating the structural, biophysical and physiological attributes of normal and diseased ion channels in brain and heart and whose mutations in human lead to major neurological and cardiovascular disorders like epilepsy, autism, atrial or ventricular fibrillation. Main Research […] Read More >
MULTI SENSOR – Multi Modal Recording System for Behavioral Tracking
It is clear today that brain activity of a restrained (or sedated) animal is completely different from that of a freely behaving animal.That is why neuroscientists are seeking to find ways to study animals freely behaving on their natural grounds.TAU’s interdisciplinary research has led to the development of the MULTI SENSOR – Multi Modal Recording […] Read More >
The Cohen Rosenthal Diabetic Hypertensive Rat (CRDH) model
The construction of the Cohen Rosenthal Diabetic Hypertensive Rat (CRDH) model was initiated nearly a decade ago by cross-breeding between the Cohen Diabetic rat (CDR) and the SHR. The CDR is a rodent model that expresses the following phenotypes: when fed regular diet, it is non-diabetic; when fed a diabetogenic diet, it invariably develops diabetes […] Read More >
Department of Biomedical Engineering – Prof. Ofer Barnea Ofer Barnea is a Professor of Biomedical Engineering at Tel Aviv University and is the Director of the Ela Kodesz Institute for Biomedical Physics and Engineering. He was the chairman of the Department of Biomedical Engineering and the chairman of the Israeli Chapter of the IEEE […] Read More >
The general goal of our laboratory is to research design and build in vitro systems that simulate cardiovascular flows, hemodynamic shear forces, and blood-tissue interaction. In addition, the laboratory conducts a wide program of numerical bio-simulations. Focus In Vitro Biological Flows. Hemodynamics. Endothelial Cell and Platelets activation. Digital Particle Image Velocimetry (DPIV). Vulnerable Plaque. Blood-Tissue […] Read More >
Cardiovascular and Physiological Assessment in Animal Models
Neufeld Cardiac Research Institute at Sheba Medical Center, Tel-Aviv University comprises a fully equipped laboratory to conduct cardiovascular and physiological experiments in small (mice, rat) and large animals (swine, sheep, calf) including heart function studies with special echocardiography system designed for small animals (Vevo660 ultrasound biomicroscope; VisualSonics), molecular imaging, pressure‐volume loop machine (Millar/Power Lab) and […] Read More >
