Diagnostics

 

15 Results were found on Technologies

Leading Researchers:
5-2017-1133

Multi-Sample Array Chip for DNA Modification Quantification

Introducing an advanced multi-sample array chip that enables precise quantification of epigenetic DNA modifications, including 5-hydroxymethylcytosine (5-hmC) and DNA damage. This technology bridges the gap between sensitivity and throughput, providing a robust platform for cancer diagnostics and personalized medicine. Unmet Need Current methods for analyzing DNA modifications suffer from limitations such as low sensitivity, high […] Read More >

Leading Researchers:
5-2016-1009

Simultaneous Analysis of Large Genomic Structural Variations and Their Epigenetic Profile

This innovative technology enables simultaneous quantification of DNA repeat sequences, large deletions, insertion, inversion and translocations, together with CpG methylation and hydromethylation patterns in individual molecules. By leveraging state-of-the-art optical mapping and fluorescence-based methylation detection, this method provides unprecedented precision in diagnosing diseases like facioscapulohumeral muscular dystrophy (FSHD) and cancers. Unmet Need Current technologies for […] Read More >

Leading Researchers:
2-2020-1415

Evaluation of Single Strand DNA Damage in Sperm Using a novel Damage Detection Technique

The Damage Detection technique is an innovative approach to assessing Single Strand DNA (ssDNA) damage by utilizing DNA repair enzymes to identify DNA adducts and single-strand breaks. Spermatozoa are characterized by high levels of DNA fragmentation, despite their condensed nuclear DNA packaging. Sublethal DNA damage, such as single strand breaks and adducts, can occur and […] Read More >

Leading Researchers:
2024-0041

Automatic Detection of Spinal Pathologies Based on MRI Scans

This study introduces an automated system for detecting spinal pathologies in MRI scans, aiming to enhance efficiency and accuracy in medical diagnostics. By leveraging deep learning, the tool can assist radiologists in identifying and classifying pathological vertebrae, potentially improving diagnostic workflows. Background MRI scans are essential for diagnosing various lumbar spine conditions, including infections, inflammations, […] Read More >

Leading Researchers:
2022-0176

Restoring Immunity Against GI Cancers

BACKGROUND GI cancers cause over 3.5 million deaths per year globally, accounting for 35% of all cancer-related deaths. Colorectal carcinoma (CRC) is the world’s second leading cause of cancer death. Current immunotherapy treatments for CRC are hamstrung by low response rate, acquired resistance, relapse and severe side effects. ImmuNovation presents a disruptive nanomodular technology utilizing […] Read More >

Leading Researchers:
2023-0080

Deep Cell-Type Deconvolution From Bulk Gene Expression Data

It is becoming clear that bulk gene expression measurements represent an average over very different cells. Elucidating the expression and abundance of each of the encompassed cells is key to disease understanding and precision medicine approaches. A first step in any such deconvolution is the inference of cell type abundances in the given mixture. To […] Read More >

Leading Researchers:
2023-082

Dense Speed of Sound Shift Imaging for Ultrasonic Thermometry

During thermal therapeutic applications such as high-intensity focused ultrasound (HIFU), hyperthermia, and cryoablation, it is crucial to monitor internal tissue temperature to provide feedback on the procedure. Non-invasive MRI techniques for thermal monitoring are limited by their availability and cost. Ultrasonic thermometry is an emerging adaptable alternative due to the advantages of ultrasound in accessibility, […] Read More >

Leading Researchers:
2-2020-1376

New Chemiluminescent Protease Probe for Rapid, Sensitive, and Inexpensive Detection of Live Mycobacterium tuberculosis

Tuberculosis (TB) is a top-ten cause of death worldwide. Successful treatment is often limited by insufficient diagnostic capabilities, especially at the point of care in low-resource settings. The ideal diagnostic must be fast, be cheap, and require minimal clinical resources while providing high sensitivity, selectivity, and the ability to differentiate live from dead bacteria.OUR SOLUTION• We […] Read More >

Leading Researchers:
5-2021-1520

Antibody-Based Biosensor Diagnostic tool for Pathogenic Bacteria Detection

UNMET NEED• Antibiotic resistance crisis is driven by extensive and inappropriate usage of antibiotics and is predicted to result in an annual death toll of 10 million people by 2050. The ability to provide a rapid and accurate surveillance and diagnosis of multiple-drug resistant (MDR) bacteria is pivotal to the efficiency of controlling the growing crisis. […] Read More >

Leading Researchers:
2-2017-1081

3D Bioprinting of Tumor Models for Personalized Drug Screening and Disease Modeling

This technology aims to provide a three-dimensional (3D) bioprinted tumor model based on natural and synthetic polymers containing several types of cells, which resembles cancer tissue. Our 3D-bioprinted tumor model has potential to predict the clinical outcome of a treatment compared to the other existing solutions, which either rely solely on genetic profiling or do […] Read More >

Leading Researchers:

GepnerLab – Health and Exercise Science

Our research focuses on understanding the impact of exercise training, combined with dietary strategies on physiology and metabolic changes across a range of populations. Specific Research interests/topics: Our primary research interests revolve around comprehending the effects of exercise training and dietary strategies on muscle mass, adipose distribution, metabolism, and performance across diverse populations. We employs […] Read More >

Prof. Arad (Abboud) Shimon

Research Interests: Signal processing of ECG waveforms. Fetal ECG monitoring. Solving the volume conductor problem in biological tissue. Modeling the electrical heart and brain activities. Lung function tests (Spirometry). Telemedicine. Electrical Impedance Tomography (Congestive Heart Failure, Osteoporosis). Bio-Impedance (brain activity). Read More >

Prof. Borenstein Elhanan

Research: Computational biology Metagenomics Human microbiome The Borenstein lab focuses on computational study of the human microbiome and of other complex microbial ecosystems. We are broadly interested in the integration of systems biology approaches, computational modeling, data science, and integrative meta-omic analysis to address fundamental questions in microbial ecology and to gain a systems-level, principled, […] Read More >

Dr. Burstein David

Dr. Burstein is a faculty member in The Shmunis School of Biomedicine and Cancer Research in the Life Science Faculty at Tel Aviv University. His research focuses on CRISPR-Cas systems, secretion systems of pathogens, and the discovery of novel antibiotic resistance genes to better understand fundamental interaction mechanisms within microbial communities and to promote their […] Read More >

Prof. Ebenstein Yuval

Our lab specializes in many areas of optical imaging and spectroscopy with emphasis on single molecule detection and development of imaging based techniques. Our research is focused on the application of novel imaging and optical detection approaches to genomic studies and biomarker detection. We are developing new spectroscopy and microscopy methodologies that combine advanced optics […] Read More >

Dr. Eliav Uzi

Read More >

Prof. Eyal Avishay

Research Interests: Photonic signal processing Propagation of light in optical fibers Polarimetric measurements Read More >

Dr. Freund Natalia

Senior Lecturer (Guest), Department of Clinical Microbiology and Immunology, Faculty of Medicine Research My laboratory is interested in understanding the molecular basis of human antibody responses to diseases. Antibodies are key components of most licensed vaccines; nevertheless many aspects of how antibodies recognize and neutralize their targets are still unknown. Pathogen-specific B cells are stimulated […] Read More >

Prof. Gannot Israel

Research Interests: Optical biopsy -optical diagnostic methods in medicine Laser tissue interaction Fibers and waveguides for medical applications Lasers and optics in medicine Read More >

Prof. Yftach Gepner

Prof. Yftach Gepner is a graduate of Ben-Gurion University’s (Beer-Sheva, Israel) in the school of Public Health (2016). His PhD Thesis established the role of combined low-carbohydrate/Mediterranean or low-fat diet, with or without physical activity on various body fat depots (mentor: Prof. Iris Shai). He then continued his training in the Department of Sport and […] Read More >

Prof. LEDERKREMER Gerardo Zelmar

Research Prof. Lederkremer’s lab has been interested in the mechanisms of protein folding and trafficking in the early secretory pathway of mammalian cells. He has focused especially on mechanisms of ER protein quality control and on recognition and delivery of misfolded proteins from the ER to the cytosolic proteasomes for ERAD. These processes are intimately […] Read More >

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