Life Sciences, Medicine, and Biotechnology
5 Results were found on Technologies
Sub Category Name
A Generic Approach Constructing an Evolutionary Stable Genetic Circuit
Any genetic circuit engineered in any organism will cause a huge metabolic load on its host, compiling the organism to manufacture numerous proteins against his own benefit thus greatly decreasing its fitness. Random mutations that arise during normal DNA replication or during DNA damage repair dictate that it’s unavoidable outcome that the genetic circuit will […] Read More >
A Dedicated Hardware for Accelerating Whole Cell Simulations of mRNA Translation for Various Biotechnological Pharma Applications
Gene expression (is a fundamental process defining all type of life where information encoded in the genetic material is used for generating proteins. Gene expression is a multi-steps process mediated by millions of intracellular biological machines (e.g. RNA polymerases, transcription factors, ribosomes, tRNAs, miRNAs), with complex interactions among them. Recently, intracellular biophysical simulations of gene […] Read More >
An Improved Fast-Growing Halophilic haloarchaeon Strain
The Challenge: Halophilic archaea (HA) are ideal for biotechnological processes because they thrive in extreme conditions, requiring minimal sterility and no freshwater. However, unlike other microorganisms like fungi, algae, and bacteria, HA are underutilized in large-scale biotechnology. Currently, HA are mostly used for producing carotenoids, like bacterioruberin, and other high-value compounds. The primary species used, […] Read More >
‘Super-Seaweeds’ Enriched with Nutritional and Health Compounds
The world population is growing and is expected to reach 10 billion by 2050. The increasing awareness of alternative natural products has led to a growing demand for plant-based goods. Currently, there’s an urgent need to enhance Earth’s capacity to support the expanding human population and address the depletion of natural resources. Humanity seeks a […] Read More >
3D Printing of 3-Layered Retina and Choroid Tissue
We present a sequential fabrication of a three-layer retina-like structure. This innovative approach aims to address the challenges associated with age-related macular degeneration (AMD) and other retinal degenerative diseases by creating a bioengineered retinal implant that mimics the natural structure and function of the human retina. Unmet Need: Age-related macular degeneration is the leading cause […] Read More >
Enhancing Plasmid Conjugation Efficiency for Transformative Biotechnological Applications
This technology enhances plasmid-based gene transfer by utilizing a leading region enriched with anti-defense genes. It enables more efficient overcoming of bacterial immune systems, improving applications in biotechnology and microbial engineering. ABSTRACT Our groundbreaking technology dramatically improves plasmid-based gene transfer by utilizing a strategically designed leading region enriched with anti-defense genes. We revealed that the […] Read More >
Simultaneous Analysis of Large Genomic Structural Variations and Their Epigenetic Profile
This innovative technology enables simultaneous quantification of DNA repeat sequences, large deletions, insertion, inversion and translocations, together with CpG methylation and hydromethylation patterns in individual molecules. By leveraging state-of-the-art optical mapping and fluorescence-based methylation detection, this method provides unprecedented precision in diagnosing diseases like facioscapulohumeral muscular dystrophy (FSHD) and cancers. Unmet Need Current technologies for […] Read More >
Multi-Sample Array Chip for DNA Modification Quantification
Introducing an advanced multi-sample array chip that enables precise quantification of epigenetic DNA modifications, including 5-hydroxymethylcytosine (5-hmC) and DNA damage. This technology bridges the gap between sensitivity and throughput, providing a robust platform for cancer diagnostics and personalized medicine. Unmet Need Current methods for analyzing DNA modifications suffer from limitations such as low sensitivity, high […] Read More >
