Medical Devices
25 Results were found on Technologies
Sub Category Name
Automated Follicle Tracking via Home-Use Ultrasound- Enhancing Fertility Monitoring with AI
While ultrasound is widely used during pregnancy, its role in pre-conception—particularly for follicle tracking—is equally critical. In fertility treatments like IVF and IUI, timing ovulation is key. This relies on frequent, accurate monitoring of follicle development. Currently, this is performed through manual 2D ultrasound scans in clinical settings, which are: Time-consuming, operator-dependent and inconvenient for […] Read More >
Touchless Short-Wave Infrared Imaging for Closed Eyes Pupillometry
Pupillometry, the measurement of pupil size and reactivity, is a critical component in neurological examinations and research. Traditional methods of assessing pupil dynamics are often limited to open-eye conditions and require direct contact, which can be impractical in various clinical settings, such as during sleep studies, anesthesia, or intensive care. The advent of touchless imaging […] Read More >
Protecting the Diabetic Neuropathic Foot Using Optimized Wound Site Foot-Loading Footwear
Diabetic neuropathic foot ulcers are a common and serious complication of diabetes, leading to significant morbidity and healthcare costs. Current offloading solutions often face challenges in effectively redistributing plantar pressure to prevent ulcer formation. In this context, the development of innovative technologies such as graded stiffness offloading insoles presents a promising approach to address this […] Read More >
New MicroRNAs as Candidates for Depression Therapy
Major depressive disorder (MDD) is a complex, common, and recurrent mental disorder (1). The current first-line treatment for MDD is selective serotonin reuptake inhibitors (SSRIs), which are antidepressant drugs that block serotonin reuptake. Two microRNA (miRNAs) molecules namely miR-30b-5p and miR-101a-3p were found to be downregulated in the raphe nuclei (RN) of mice following chronic […] Read More >
Tailorable Sensors for Enzymatic Activity Based on Single-Walled Carbon Nanotubes with a Responsive Corona of Dendron–Polymer Hybrids
We have developed highly modular amphiphilic polymer-dendron hybrids composed of hydrophobic dendrons and hydrophilic linear polymer (e.g. polyethylene glycol (PEG)) that can be synthesized with a high degree of structural precision for suspending SWCNTs in an aqueous solution. Utilizing the susceptibility of the dendritic block of these amphiphiles toward enzymatic degradation, we demonstrated the ability […] Read More >
Rationally Designed Functionalization of Single-Walled Carbon Nanotubes for Real-Time Monitoring of Cholinesterase Activity and Inhibition in Plasma
We employ a fluorometric approach to monitor the activity and inhibition of cholinesterase (CHE) enzymes in blood plasma. We utilize near-infrared (NIR) fluorescent single-walled carbon nanotubes (SWCNTs) as probes strategically functionalized with myristoylcholine (MC), which is a substrate for CHE. The fluorescence intensity of MC-suspended SWCNTs undergoes a significant decrease upon interaction with CHE, attributed […] Read More >
Dense Speed of Sound Shift Imaging for Ultrasonic Thermometry
During thermal therapeutic applications such as high-intensity focused ultrasound (HIFU), hyperthermia, and cryoablation, it is crucial to monitor internal tissue temperature to provide feedback on the procedure. Non-invasive MRI techniques for thermal monitoring are limited by their availability and cost. Ultrasonic thermometry is an emerging adaptable alternative due to the advantages of ultrasound in accessibility, […] Read More >
Veye AI-Based Non-Invasive Blood Test for Remote Care
The Clinical Need: Non-invasive blood testing for remote care • Blood count test is the most common clinical test routinely done in billions of patients,• Blood sampling procedure has not significantly changed over a century, requiring an invasive bloodcollection under sterile conditions and laboratory analysis.• Limited accessibility and testing frequency may be life-threatening• Highly invasive […] Read More >
Jellyfish׳ Collagen-Based Smart Wound Dressing with Antibacterial Properties
Collagen-based dressing in wounds greatly benefits the healing process. Unfortunately, most collagen is extracted from bovine tissues, which bears a significant risk of transmitting various biological contaminations. Moreover, the collagen extraction process from bovine tissue involves time and cost-consuming steps, reducing the total collagen yield and increasing the overall cost of goods. In addition, the […] Read More >
Anti-Oxidation Agent to be Incorporated Into Cosmetics Leading to More Stable and Longer Shelf-Life Products
Oxidation is the reaction of Oxygen with a wide array of reactants. In cosmetics, product oxidation leads to spoilage of ingredients used in the manufacturing products, the inactivation of oxygen-sensitive enzymes, shortening of product shelf-life, and discolorations of end-product. Self-assembling peptide-based hydrogels are simple hydrogels that can be combined with a wide variety of ingredients […] Read More >
Data Driven Algorithm For Visualizing Myelin in The Human Brain
Quantification of myelin content in the human brain is the key for early disease detection and for assessing treatment response in patients with neurodegenerative diseases. However, it has remained challenging due to lack of a reliable method for probing sub-voxel features from clinical MRI data. We developed a data-driven algorithm that accurately converts clinical MRI […] Read More >
Early and Accurate Categorization and Identification of the Pathogen Infection
The detection of pathogens is important to the prevention and identification of health problems and for a better lifestyle. The growth of this market is chiefly credited to the high prevalence of infectious diseases, technological advances, growing concern for safety; government initiatives, bioterrorism surveillance and high healthcare expenditure are expected to provide the required impetus […] Read More >
High resolution deep tissue imaging of turbid media
Technology Imaging through turbid media such as occluding body fluids (e.g. blood, urine, CSF) is restricted due to strong scattering. In applications such as intravascular optical imaging applications clearing of the imaging path (the lumen) are done by, e.g., locally stopping blood flow. The technology utilizes guided shaped light for minimally-invasive Angioscopy without the necessity […] Read More >
Interferometric phase microscopy for label-free morphological evaluation of sperm cells
Portable, compact, add-on Interferometric Phase Microscope module An optical module and software package which optically compresses several interferometric images into a single camera image and thus provides extended interferometric the field of view (FOV). Records more interferometric information on the same amount of camera pixels. ApplicationsMedical industry In-vitro diagnostics -Measuring quantitative thickness profiles of biological […] Read More >
A smartphone based psychiatrist-aid system to monitor and prevent recurring illnesses
Lifegraph enables early detection of disease deterioration in mental health patients,using proprietary machine-learning algorithms applied to data collected from thesmartphone sensors.VISIONImproving lives of patients with mental disorders and decreasing the burden of disease on patients,their families and society as a whole.NEED AND MARKET POTENTIALMental disorders are a leading cause for loss of productivity and hospital […] Read More >
An Add-On Optical Interferometer Chamber to Phase Microscopes for Sub-Nanometer 3D and Dynamic Information
TechnologyAn add-on optical module for microscopes allowing for single frame and dynamic capture of amplitude and phase profiles of transparent or semi-transparent biological and non-biological samples. This easyto-use interferometric device is simply positioned in the camera port of a conventional inverted microscope, enabling quantitative structural, thickness and refractive index measurements in a noncontact, label-free manner. […] Read More >
METHODS AND KITS FOR DETERMINING PREDISPOSITION TO DEVELOP KIDNEY DISEASES
Many rare kidney disorders exhibit a monogenic, Mendelian pattern of inheritance. Population-based genetic studies have identified many genetic variants associated with an increased risk of developing common kidney diseases. Strongly associated variants have potential clinical uses as predictive markers and may advance our understanding of disease pathogenesis. These principles are elegantly illustrated by a region […] Read More >
Self Assembled Peptide Hydrogel
The Technology A breakthrough Self Assembled Peptide Hydrogel (SAPH) has been developed. SAPH is a safe, self-assembled, biocompatible, remarkably strong hydrogel with modulated stability that is suitable for various medicinal and cosmetic applications. SAPH is based on the highly efficient self-assembly of the short aromatic peptides diphenylalanine. The discovery and development of SAPH is the […] Read More >
Novel Class of Turn-ON Near-Infrared Probes for Diagnosis and Imaging of Inflammation and Cancer
Complete tumor removal during surgery has a great impact on patient survival. To that end, the surgeon should detect the tumor, remove it and validate that there are no residual cancer cells left behind. Residual cells at the incision margin of the tissue removed during surgery are associated with tumor recurrence and poor prognosis for […] Read More >
Low Frequency Nanobubbles-Enhanced Ultrasound Mechanotherapy for Noninvasive Cancer Surgery
A unique theranostic ultrasound-based technology for low-energy mechanical ablation of tissues. Noninvasive ultrasound surgery can be achieved using focused ultrasound to locally affect the targeted site without damaging intervening tissues. Mechanical ablation and histotripsy use short and intense acoustic pulses to destroy the tissue via a purely mechanical effect. Here we show that coupled with […] Read More >
A Lensless Polarization Camera
Polarization imaging is a technique that creates a pixel-map of the polarization state in a scene. Although invisible to the human eye (and for most conventional cameras), polarization can assist various sensing and computer vision tasks. Existing polarization cameras acquire the additional modality using either spatial or temporal multiplexing, which increases the camera volume, weight, […] Read More >
Explainable AI (XAI)
One important challenge in machine learning is the “black box” problem, in which an artificial intelligence reaches a result without any humans being able to explain why. This problem is typically present in deep artificial neural networks, in which the hidden layers are impenetrable. To tackle this problem, our researchers have introduced the notion of explainable […] Read More >
Advanced Sensitivity in Point-of-Care Diagnostics: Electrokinetic Preconcentration Technology
As is evident from the lateral-flow-assay (LFA) that became so popular with detection of Corona virus, there is an urgent need to increase the sensitivity of detection of both point-of-care (POC) and self-testing (for example, used by individuals at home) devices. Lateral flow kits result in relatively low detection limit as only a small fraction […] Read More >
Microfluidic Flow-meter and Sensor for Drug Delivery Applications
The current structure of medical pumps does not allow real-time measurement of different parameters of drug delivery in general and low flow rates (μL/min) in particular. The current structure wherein only indirect measurements are performed (commonly pressure) makes it difficult to detect failures (e.g. air bubbles, occlusion, infiltration) in real-time on the one hand and […] Read More >
METHOD FOR GENERATION OF CONTROLLED THz WAVES
We present a method for the generation of THz pulses with tailored temporal shape from nonlinear metasurfaces. The method is based on single-cycle THz emission by the metasurface inclusions. We show that the spatial amplitude and phase structure of the nonlinear response is mapped to the temporal shape of pulses emitted at certain angles. We […] Read More >
