Neuroscience
18 Results were found on Technologies
Sub Category Name
Virtual Robot Facilitator for Small Group Discussions in an Online Environment
In the post-COVID era, many activities has transferred to a collaborative online environment. Both in the education system as well as the workplace, many classes and meetings are held in videoconferencing of small groups. These have been repeatedly shown to be the most effective mode of operation. The problemOnline meetings of small groups tend to […] Read More >
Targeting Human Brain Cells With Adeno-Associated Virus (AAV) for a Prospective Therapeutic Approach
The AAV therapeutic approach for various central nervous system (CNS) illnesses has been rapidly growing. Unfortunately, existing present technologies utilize AAV administration that is injected locally into the brain. This process requires a high level of expertise and is not applicable in more diffused brain targets like cortex and stiratum. Systemic administration of AAV vectors through […] Read More >
Gaze-Contingent Music Reward Therapy for Social Anxiety Disorder
Patients with social anxiety disorder exhibit increased attentional dwelling on social threats, providing a viable target for therapeutics. We purpose a novel gaze-contingent music reward therapy for social anxiety disorder designed to reduce attention dwelling on threats Attention bias modification refers to a novel group of treatments grounded in cognitive neuroscience targeting aberrant threat-related attention […] Read More >
Homocysteine fibrillar assemblies display crosstalk with Alzheimer’s disease amyloid polypeptide
High levels of homocysteine (Hcy) are reported as a risk factor for Alzheimer’s disease (AD). Correspondingly, inborn hyperhomocysteinemia is associated with an increased predisposition to the development of dementia in later stages of life. Furthermore, despite the apparent association between protein aggregation and AD, attempts to develop a therapy that targets explicitly this process have […] Read More >
Development of Alzheimer Disease therapy based on counteracting the pathological effects of ApoE4
Alzheimer’s disease (AD) is the most common cause of dementia and is the outcome of progressive brain cells death. Due to the disorder’s heterogeneity and in view of the variety of pathological mechanisms inducing the disease we have undertaken an innovative – science based (Animal model) approach, which is presented here. Our unique approach […] Read More >
iPONT- Israeli Platform for Online Neuropsychological Testing
ObstaclesTwo main obstacles in testing the cognitive status of patients with neurological disorders are: 1. Small and Unrepresentative Samples: The sample size of studies is small and not diverse, frequently with 50 or fewer participants from the same geographic area. 2. Time Required: It can take significant time to undertake a single study, let alone […] Read More >
Deep Brain Stimulation of Thalamic Nucleus Reuniens as a New Therapeutic Tool to Prevent Neuronal and Cognitive Dysfunctions in Alzheimer’s Disease
We utilize the basic concepts of control theory and an integrative approach which spans brain-state, neural circuit, synaptic and molecular levels to boost cognitive resilience to AD pathology1,2. UNMET NEED There is no efficient, disease-modifying therapy at present for Alzheimer’s disease (AD). Even the most successful, recently FDA approved anti-amyloid drug lecanemab shows a great […] Read More >
Targeting Mitochondrial IGF-1 Receptors as Therapy for Neurodevelopmental Disorders
Neurodevelopmental brain disorders (NDDs) pose an immense burden on both the families of patients and the health and educational systems, without any effective therapies. We propose, based on our novel findings that are supported by recent clinical data, a potential gene therapy strategy that might restore the brain activity of patients to a healthy regime. […] Read More >
