24 Results were found on Technologies


An Effective Sema3A Antibody as a Therapy for Optic Nerve Neurodegenerative Diseases

Glaucoma and ischemic or neuro-degenerative diseases of the optic nerve lead to vision loss and blindness. These pathologies are associated with progressive apoptosis of the retinal ganglion cells (RGC), a process which involves expression of... Read More >


Specific DNA editing of Apo-E4 gene, the main risk factor in Alzheimer disease

THE NEED The current approach to the development of treatment of Alzheimer's disease (AD), which is the most prevalent form of dementia of the elderly, has not produce any clinically meaningful results. The most prevalent... Read More >

Leading Researchers:

Pioneering Protein Replacement Therapy for ADNP Syndrome and Neurodevelopmental Disorders

UNMET NEED ADNP, discovered by Professor Gozes, is subject to “spontaneous” mutations resulting in the ADNP syndrome (debilitating outcomes, developmental delays, motor and cognitive dysfunctions, autistic traits). ADNP is a leading gene... Read More >

Leading Researchers:

Whole Brain Visualization of Distinct Cortical Layers by MRI

The TechnologyAn MRI platform including an imaging protocol and analysis software enabling in-vivo visualization, characterization and measurement of the distinct layers of the human cortex including width in 3D. The imaging protocol utilizes... Read More >

Leading Researchers:

MIR126-5P For ALS Treatment

Perlson and his team uncovered a novel mechanism that contributes to neurodegeneration that takes place in ALS models. Using both in vitro and in vivo ALS models, we demonstrated that alterations in miR126-5p, which regulates the secretion of... Read More >

Leading Researchers:

Deletion of Caspase-6 using CRISPR improves the memory function in models of Alzheimer disease

THE NEED Currently, there is no cure for Alzheimer'. Although caspase-6 was demonstrate to play a role in the pathology there is no clinical available caspase-6 inhibitors. Caspases, a family of cysteine proteases, are major mediators... Read More >

Leading Researchers:

Novel Biomarker for Schizophrenia

Novel Biomarkers for Schizophrenia RNA editing is thought to be a major contributor to brain development and function [1]. A-to-I RNA editing is an enzymatic conversion of genomically encoded Adenosine to Inosine that is recognized as... Read More >

Leading Researchers:

Support Medium For 3d Printing Of Biomaterials

Building materials for 3D bioprinting generally possess weak mechanical properties and thus must be supported during fabrication in order to prevent the collapse of the printouts. Here we present a uniquely formulated media used to support... Read More >

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Synthetic 9-cis beta Carotene for treatment of retinal degeneration

9-cis β-carotene-rich is an effective treatment for retinal diseases. Its production in algae was a bottleneck of clinical trials. Now there is a new a synthetic method for its production. BACKGROUNDAge related macular degeneration (AMD) and... Read More >

Leading Researchers:

A smartphone based psychiatrist-aid system to monitor and prevent recurring illnesses

Lifegraph enables early detection of disease deterioration in mental health patients,using proprietary machine-learning algorithms applied to data collected from thesmartphone sensors.VISIONImproving lives of patients with mental disorders and... Read More >