Neuroscience

 

20 Results were found on Technologies

Leading Researchers:
10-2007-105

BBS Ab -A novel target for Alzheimer's and ALS immunotherapy

THE TECHNOLOGYBBS is a monoclonal antibody that binds specifically and blocks beta-secretase (BACE1) cleavage site on its substrate, APP. BBS inhibits Ab production, a hall-mark of AD and other neurodegenerative diseases such as ALS.The... Read More >

Leading Researchers:
10-2019-1237

A Promising New Target Epitope for the Treatment of Neurodegenerative Diseases

• GSK‐3, is a promising drug target for treating multiple pathological disorders like Alzheimer’s diseases, Fragile X and Huntington’s disease. • Most GSK‐3 inhibitors that were developed function as... Read More >

Leading Researchers:
10-2011-259

Immunotherapy for Stroke and Cognition in a Cerebral Amyloid Angiopathy Animal Model

Cerebrovascular dysfunction is a fundamental part of the pathology of several neurodegenerative diseases and rated as one of the most prominent cause for dementia. Cerebral amyloid angiopathy (CAA) results in intra-parenchymal and subarachnoid... Read More >

Leading Researchers:
2-2016-978

Neuromuscular junction Multi-electrode arrays

Neuromuscular Junction - multi electrode arrays (NMJ-MEA) – a novel drug high-throughput synapse activity functional screening device Finding efficient treatments to neurodegenerative diseases and spinal cord injury has not yet been achieved... Read More >

Leading Researchers:
10-2020-1360

Targeting Human Brain Cells With Adeno-Associated Virus (AAV) for a Prospective Therapeutic Approach

The AAV therapeutic approach for various central nervous system (CNS) illnesses has been rapidly growing. Unfortunately, existing present technologies utilize AAV administration that is injected locally into the brain. This process requires a high... Read More >

2-2019-1277

An Effective Sema3A Antibody as a Therapy for Optic Nerve Neurodegenerative Diseases

Glaucoma and ischemic or neuro-degenerative diseases of the optic nerve lead to vision loss and blindness. These pathologies are associated with progressive apoptosis of the retinal ganglion cells (RGC), a process which involves expression of... Read More >

Leading Researchers:
8-2016-1043

Gaze-Contingent Music Reward Therapy for Social Anxiety Disorder

Patients with social anxiety disorder exhibit increased attentional dwelling on social threats, providing a viable target for therapeutics. We purpose a novel gaze-contingent music reward therapy for social anxiety disorder designed to reduce... Read More >

Leading Researchers:
2-2022-1756

Homocysteine fibrillar assemblies display crosstalk with Alzheimer’s disease amyloid polypeptide

High levels of homocysteine (Hcy) are reported as a risk factor for Alzheimer’s disease (AD). Correspondingly, inborn hyperhomocysteinemia is associated with an increased predisposition to the development of dementia in later stages of life... Read More >

Leading Researchers:
2-2018-1175

Support Medium For 3d Printing Of Biomaterials

Building materials for 3D bioprinting generally possess weak mechanical properties and thus must be supported during fabrication in order to prevent the collapse of the printouts. Here we present a uniquely formulated media used to support... Read More >

10-2013-549

Novel specific disease-modifying PERK activator for Huntington’s disease

There is no efficient therapy at present for Huntington’s disease (HD) nor for any other neurodegenerative disease, including Alzheimer’s and Parkinson’s diseases. No disease-modifying approaches exist. Gene therapy-based clinical trials have... Read More >