Peptides / Proteins
17 Results were found on Technologies
Sub Category Name
Immunotherapy for Stroke and Cognition in a Cerebral Amyloid Angiopathy Animal Model
Cerebrovascular dysfunction is a fundamental part of the pathology of several neurodegenerative diseases and rated as one of the most prominent cause for dementia. Cerebral amyloid angiopathy (CAA) results in intra-parenchymal and subarachnoid bleeding, which is caused by cerebrovascular amyloid deposits and multiple infarcts, and can lead to hemorrhagic stroke and cognitive impairment (Greenberg et […] Read More >
Self Assembled Peptide Hydrogel
The Technology A breakthrough Self Assembled Peptide Hydrogel (SAPH) has been developed. SAPH is a safe, self-assembled, biocompatible, remarkably strong hydrogel with modulated stability that is suitable for various medicinal and cosmetic applications. SAPH is based on the highly efficient self-assembly of the short aromatic peptides diphenylalanine. The discovery and development of SAPH is the […] Read More >
Improved Calcitonin-based Therapeutics
TechnologyThe aggregation site on human calcitonin has been identified, paving the way for development of specific inhibitors of calcitonin amyloid fibril formation. Such inhibitors will enable development of improved calcitonin therapeutics as well as greatly facilitate in vitro calcitonin manipulations. The NeedThe therapeutic use of human calcitonin is severely limited by its tendency to associate […] Read More >
Self-Assembling Aromatic di-Peptide Materials for Cosmetic Applications
TechnologyOrganic, aromatic di-peptide self-assemble into close-caged structures of tubes, spheres and hydrogels. These exhibit excellent properties such as stability, solubility, transparency and rigidness alongside the basic peptide features utilized in cosmetics. The materials can be prepared as powder or hydrogel and be easily mixed with common cosmetic foundations. In addition to these native characteristics, methods […] Read More >
Molecular Electronics and Transistors based on Peptide Nanostructures
The TechnologyProprietary peptide nanostructures1 can be readily fabricated on various surfaces including electrodes2,4. A physical vapor deposition method (PVD) allows the precise control on the molecular dimensions of the structures using industry standard techniques. These nanostructures were used to fabricate metallic nanowires1 as well as trilayer metal-peptide-metal nano-cables3. Electrodes and storages devices were modified with […] Read More >
PNA – Self Assembled peptide nanostructures for OLED / Security applications
TechnologyWe developed nanostructures based on Peptide-Nucleic Acid (PNA) derivatives which show highly promising performance characteristics. The unique electroluminescence/photoluminescence materials can be used as emissive materials in manufacturing Organic Light-Emitting Diodes (OLED) with high emission efficiencies, tunable colors, and improved charge-transport and film-forming properties. The NeedSignificant progress has been made over the past decade in producing […] Read More >
Unique Cocktail of Neutralizing Antibodies against SARS-CoV-2
We have identified eight potent neutralizing antibodies (mAbs) from recovered COVID-19 patients for COVID-19 treatment. These antibodies may be used as pre-exposure prophylaxis, i.e., as short-term protection from infection for populations at risk and highly exposed medical teams or those that did not develop enough antibodies post vaccinationUNMET NEEDThe COVID-19 pandemic caused by SARS-CoV-2, has […] Read More >
Novel Anti-Tumor Response treatment targeting ErbB receptors and Nucleolin interactions
ErbBs subfamily receptors are mediators of cell growth signals. They have long been associated with a wide variety of lung, ovarian, colon, breast, prostate, and other carcinomas. Nucleolin is a major nucleolar protein of growing eukaryotic cells and is present on the cell surface of a range of cancers. Recently, a robust oncogenic interaction between […] Read More >
Protection of Oxygen-Sensitive-Enzymes by Peptide Hydrogel
Molecular oxygen (O2) is a highly reactive oxidizing agent harmful to many biological and industrial systems. A simple encapsulation in a protective aqueous environment of O2 -sensitive reactions is of need. Self-assembling peptide-based hydrogels are simple hydrogels that can be combined with a wide variety of reagents and are able to encage O2 and significantly limit its […] Read More >
Anti-Oxidation Agent to be Incorporated Into Cosmetics Leading to More Stable and Longer Shelf-Life Products
Oxidation is the reaction of Oxygen with a wide array of reactants. In cosmetics, product oxidation leads to spoilage of ingredients used in the manufacturing products, the inactivation of oxygen-sensitive enzymes, shortening of product shelf-life, and discolorations of end-product. Self-assembling peptide-based hydrogels are simple hydrogels that can be combined with a wide variety of ingredients […] Read More >
