43 Results were found on Technologies
Many rare kidney disorders exhibit a monogenic, Mendelian pattern of inheritance. Population-based genetic studies have identified many genetic variants associated with an increased risk of developing common kidney diseases. Strongly associated... Read More >
The Technology The human asialoglycoprotein receptor (ASGPR) is expressed on the sinusoidal membrane of hepatocytes and serves in the clearance of asialoglycoproteins from the plasma. A soluble form of the ASGPR, termed sH2a, is formed by... Read More >
TechnologyThe aggregation site on human calcitonin has been identified, paving the way for development of specific inhibitors of calcitonin amyloid fibril formation. Such inhibitors will enable development of improved calcitonin therapeutics as... Read More >
TechnologyStabilized human IAPP (hIAPP) oligomers were used for the development of active immunization of type 2 diabetes. This promising novel approach for the treatment of type 2 diabetes is doable due to the establishment of a new protocol for... Read More >
The invention is an image processing method of light microscopy images for the purpose of quantifying density of cells in cultures . A grayscale image of a cell culture is digitally captured using a light microscope and a CCD camera... Read More >
Collaboration with Dr Shlomit Mesilaty, Dr Yair Anikster, Prof Ido Wolf Metabolic Enzymatic Laboratory, Sheba Medical Center. Bone metastasis is a major clinical concern that can cause severe pain, bone fractures, spinal cord... Read More >
Glaucoma and ischemic or neuro-degenerative diseases of the optic nerve lead to vision loss and blindness. These pathologies are associated with progressive apoptosis of the retinal ganglion cells (RGC), a process which involves expression of... Read More >
Peripheral nerve and spinal cord injuries are debilitating conditions. Annually, the number of peripheral nerve incidences is 13.9 per 100,000 people and nearly 500,000 people worldwide suffer from spinal cord injury (SCI). Consequently, the... Read More >
While most groups are working on the development of drugs and vaccines for SARS-CoV-2, we aim at finding a short-term solution to be ready for use ASAP. Here, we propose a healthy dietary supplement (a combination of several dietary supplements)... Read More >
An oncolytic virus for melanoma tumors with defective interferon signaling, designed as a potent, specific and safe therapy. Promising in-vivo murine melanoma model shows potential for development as a mono or an add-on to chemotherapy or... Read More >