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40 Results were found on Technologies
Sub Category Name
Dendritic Cell-Targeted Nanovaccine for SARS-CoV-2 with Incorporated Immune Potentiators
During the SARS-CoV-2 pandemic, nanoscale vaccine technologies (e.g., mRNA vaccines) have proven superiority over conventional vaccines in terms of production speed and modularity. Unfortunately, the restricted global distribution results in... Read More >
SK4 K+ channel blockers: a new treatment for cardiac atrial fibrillation
We discovered a previously unidentified target in the heart, namely the SK4 calcium-activated K+ channels, which are functionally expressed in pacemaker cells as well as in atrial and ventricular cardiomyocytes. They are crucial for proper cardiac... Read More >
Immunotherapy for Stroke and Cognition in a Cerebral Amyloid Angiopathy Animal Model
Cerebrovascular dysfunction is a fundamental part of the pathology of several neurodegenerative diseases and rated as one of the most prominent cause for dementia. Cerebral amyloid angiopathy (CAA) results in intra-parenchymal and subarachnoid... Read More >
Glioblastoma Regression by Regulating Astrocytes' Immunometabolic Signaling
Malignant brain tumors are the cause of a disproportionate level of morbidity and mortality among cancer patients, an unfortunate statistic that has remained constant for decades. Despite considerable advances in the molecular characterization of... Read More >
Unique Cocktail of Neutralizing Antibodies against SARS-CoV-2
We have identified eight potent neutralizing antibodies (mAbs) from recovered COVID-19 patients for COVID-19 treatment. These antibodies may be used as pre-exposure prophylaxis, i.e., as short-term protection from infection for populations at risk... Read More >
Homocysteine fibrillar assemblies display crosstalk with Alzheimer’s disease amyloid polypeptide
High levels of homocysteine (Hcy) are reported as a risk factor for Alzheimer’s disease (AD). Correspondingly, inborn hyperhomocysteinemia is associated with an increased predisposition to the development of dementia in later stages of life... Read More >
Therapeutic Vaccine for the Treatment of Cancer
An active cancer vaccine strategy targeting tumor-associated carbohydrate antigens expressed on tumor cells using biomimetic glyconanoparticles generated from unique red blood cells. The resulting sustained immune response inhibits tumor... Read More >
Controlled-release formulation in double microfluidic encapsulated emulsion for spinal cord injury, Ischemic Stroke and TBI
UNMET NEEDNeurotrauma causes accumulation of excess toxic glutamate and neurological damage. Anti-glutamatergic treatments have failed to reduce CNS (Central nerve system) glutamate levels after SCI, and there is no clinically available emergency... Read More >
Biomarkers for Risk Assessment in Colorectal Cancer Patients
Mortalin (also known as GRP75 and mitochondrial stress protein 70) is a ubiquitously expressed mitochondrial chaperone related to the cytosolic heat shock protein 70 (HSP70). It protects cells from senescence and apoptosis and is overexpressed in... Read More >
Automated Processing Of Non-Invasive Thermal Imaging Of Organ-Specific Diseases To Detect Inflammation And Vascular Dysfunction
During the COVID-19 worldwide pandemic, rapid and sensitive screening tools for SARS-CoV2 infection were defined critical for limiting the spread of COVID-19 and for allocating national resources properly. Researchers have developed and... Read More >
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