37 Results were found on Technologies
TechnologyThe aggregation site on human calcitonin has been identified, paving the way for development of specific inhibitors of calcitonin amyloid fibril formation. Such inhibitors will enable development of improved calcitonin therapeutics as... Read More >
TechnologyStabilized human IAPP (hIAPP) oligomers were used for the development of active immunization of type 2 diabetes. This promising novel approach for the treatment of type 2 diabetes is doable due to the establishment of a new protocol for... Read More >
The invention is an image processing method of light microscopy images for the purpose of quantifying density of cells in cultures . A grayscale image of a cell culture is digitally captured using a light microscope and a CCD camera... Read More >
The Technology The human asialoglycoprotein receptor (ASGPR) is expressed on the sinusoidal membrane of hepatocytes and serves in the clearance of asialoglycoproteins from the plasma. A soluble form of the ASGPR, termed sH2a, is formed by... Read More >
Many rare kidney disorders exhibit a monogenic, Mendelian pattern of inheritance. Population-based genetic studies have identified many genetic variants associated with an increased risk of developing common kidney diseases. Strongly associated... Read More >
Herpes simplex virus infection is commonly known as herpes. The two types of herpes simplex virus are HSV-1 (known to cause orofacial disease such as cold sores) and HSV-2 (causes genital infections). Over 80% of herpes infections is asymptomatic... Read More >
Anti-cancer NanoTherapyUtilizing unique nano-technology to develop targeted combination nanomedicines that were shown to be synergistic, effective and safe for treating cancer TechnologyWe have developed a new platform technology for the... Read More >
Interactions between programmed cell death ligand 1 (PD-L1) and programmed cell death protein 1 (PD-1) lead to the evasion of cancer cells from an efficient immune response. The inhibition of PD-L1/PD-1 has prevented or reversed exhausted T cells,... Read More >
Glaucoma and ischemic or neuro-degenerative diseases of the optic nerve lead to vision loss and blindness. These pathologies are associated with progressive apoptosis of the retinal ganglion cells (RGC), a process which involves expression of... Read More >
Aniridia is a panocular disease causing progressive severe visual impairment and blindness. The disease is characterized by abnormal development of almost all eye structures, caused by dominantly inherited heterozygous mutations in primarily the... Read More >