Polymers

 

4 Results were found on Technologies

10-2008-86

Targeting Bone Neoplasms and Other Cancers with Novel Combined Anticancer and Anti-Angiogenic Polymer Therapeutics

Anti-cancer NanoTherapyUtilizing unique nano-technology to develop targeted combination nanomedicines that were shown to be synergistic, effective and safe for treating cancer TechnologyWe have developed a new platform technology for the treatment of cancer and bone metastases using combined targeted nano-sized polymers that deliver chemotherapeutics creating a new class of effective and safer molecules. The novel […] Read More >

Leading Researchers:
10-2019-1337

Anti-Cancer Nanotherapy: Targeted Potent Conjugated BRAF/MEK Inhibitors

In the last decade, deep understanding of key oncogenes and signaling pathways, involved in cancer pathogenesis and progression were achieved, leading to new treatment options. However, the number  of patients with metastatic melanoma continue to rise. This may be attributed to the prolonged life-span of cancer patients with primary tumors, enabling metastatic spread later on. […] Read More >

Leading Researchers:
11-2021-1528

Jellyfish׳ Collagen-Based Smart Wound Dressing with Antibacterial Properties

Collagen-based dressing in wounds greatly benefits the healing process. Unfortunately, most collagen is extracted from bovine tissues, which bears a significant risk of transmitting various biological contaminations. Moreover, the collagen extraction process from bovine tissue involves time and cost-consuming steps, reducing the total collagen yield and increasing the overall cost of goods. In addition, the […] Read More >

Leading Researchers:
2-2022-1756

Homocysteine fibrillar assemblies display crosstalk with Alzheimer’s disease amyloid polypeptide

High levels of homocysteine (Hcy) are reported as a risk factor for Alzheimer’s disease (AD). Correspondingly, inborn hyperhomocysteinemia is associated with an increased predisposition to the development of dementia in later stages of life. Furthermore, despite the apparent association between protein aggregation and AD, attempts to develop a therapy that targets explicitly this process have […] Read More >

Prof. Fleminger Gideon

Our laboratory is engaged in the study of structure-function relationships in proteins and peptides involved in biorecognition processes. In these studies we apply sophisticated separation methods for the purification with advanced methods of structural analysis of these materials.  Specific research activities include: Structure-function relationships in Ca+2-binding proteins:  We are engaged in the study of the […] Read More >

Dr. Leikin-Frenkel Alicia

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Prof. Jonathan Leor

Professor Leor received an M.D. degree from Tel-Aviv University, continued training in cardiovascular medicine at the Sheba Medical Center, and completed his post doctorate training at the University of Southern California, Los Angeles, under Robert A. Kloner, M.D., Ph.D. Today, his laboratory’s research focuses on infarct repair and the heart’s lack of intrinsic regenerative ability. […] Read More >

Prof. Margalit Rimona

Research Interests 1. Micro- and nano-particulate drug delivery technologies for topical, regional and systemic applications:  Our efforts in the drug delivery arena focus on two drug delivery technologies, one veteran and one novel, that are inventions of our group. These technologies each yield, micro and nano sized particles that are composed of biomaterials with particular […] Read More >

Prof. Satchi-Fainaro Ronit

Our research interests include investigations related to tumor biology, tumor dormancy, mechanism of action of angiogenesis inhibitors, self-assembly of polymeric architectures and novel approaches to target cancer. Throughout, we have maintained an interest in understanding the biological rationale for the design of polymer therapeutics suitable for transfer into clinical testing. Our primary interests are the molecular […] Read More >

Prof. Shabat Doron

Research Self-immolative dendrimers are unique structural molecules that can release all of their tail units, through a domino-like chain fragmentation, which is initiated by a single cleavage at the dendrimer’s core. Incorporation of drug molecules as the tail units and an enzyme substrate as the trigger, can generate a multi-prodrug unit that is activated with […] Read More >

Prof. Zilberman Meital

Active implants can provide life-giving help to many systems in the body. When made of a biodegradable polymer, the degradation of such implants occurs by hydrolytic cleavage and the end products (carbon dioxide and water) are non-toxic. These implants can remain intact in the body for a predicted period of time – from weeks to […] Read More >

Leading Researchers:
12-2011-205

Lipid Solutions and Animal Model

SERVICES“ Lipid Solutions” Prof. Alicia Leikin-Frenkel “Lipid Solutions” covering:1. Expert support for questions on: lipid metabolism, isolation, identification and quantitation of lipids in different species and different matrixes.2. Guidance to discover the pathway to physiological and biochemical implications following overexpressed or suppressed gene linked to lipids.3. Counseling to analyze lipids in:• Simple molecules: fatty acids: Saturated, Monounsaturated n7, n9, Polyunsaturated: […] Read More >

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