Research topic: Elucidating the decoding mechanisms of ubiquitin signals and their significance in neurodegenerative diseases

Research methods: Biophysical measurements including SPR, AUC, MST and SEC, X-ray crystallography, Bioinformatics, Biochemistry and bacterial genetics

Projects in the lab include:

1. Molecular mechanisms that regulate membrane protein trafficking and Parkinson’s disease

1. Mechanisms for regulation of sodium / potassium channels and dopamine transporter.

1. The molecular basis of the involvement of the ubiquitin E3-ligases Ube3A and Ube3B in autism

1. The involvement of ubiquitin-receptors in amyloid formation.