Prof. Shaked heads the Biomedical Optical Microscopy, Nanoscopy and Interferometry Research Group, a large experimental group performing a multidisciplinary research involving optical engineering, imaging and sensing in biological systems, optical therapy, and biophysics. Specific interests of research include: biomedical optical microscopy and nanoscopy, optical interferometric systems (including interferometric phase microscopy and optical coherence tomography), optical imaging and therapy using nano-particles in biological cells, optical signatures of cancer and fertility problems, and three-dimensional optical imaging and holography for biomedical applications.