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258 Results were found on Technologies

Leading Researchers:
2023-0069

3D Multi-Sensory Platform for Advanced In Vitro Models

UNMET NEED As biological models continue to evolve from traditional 2D cultures to complex 3D tissues, organoids, and bioprinted constructs, there is a growing need for sensing technologies capable of monitoring functionality within these physiologically relevant systems. Current sensing platforms, including conventional MEA and TEER systems, are largely limited to two-dimensional measurements. OUR SOLUTION Researchers […] Read More >

Leading Researchers:
2023-0089

Write-and-Read: Programmable Epigenomic Sequencing via Synthetic DNA Labeling

DESCRIPTION A chemo-enzymatic platform that actively encodes new biological information into DNA before nanopore sequencing — enabling simultaneous genetic and epigenomic readout from a single molecule, in a single run. By installing synthetic base modifications at targeted sites, the platform converts epigenetic events (5-hydroxymethylcytosine, chromatin accessibility, DNA damage) into distinct, machine-readable electrical signals without bisulfite […] Read More >

Leading Researchers:
2023-0128

OGP: A CB2 Agonist Enhancing CAR-T Therapy

CAR-T therapies show promising clinical responses, yet many patients relapse due to the immunosuppressive tumor microenvironment (TME). Multiple Myeloma remains largely incurable. OUR SOLUTION Osteogenic growth peptide (OGP), a selective CB2 agonist, enhances anti-tumor immunity by reducing immunosuppressive myeloid cells and boosting cytotoxic T-cell activity. In preclinical studies, OGP demonstrated synergistic activity with CAR-T therapy, […] Read More >

Leading Researchers:
7-2018-1203

Peak-to-Average Power Ratio (PAPR) Reduction for High-Speed Communications

Description and Need Modern data communication demands ever-increasing transmission rates, with current standards targeting 100 Gbps to 400 Gbps. As symbol rates rise, intersymbol interference (ISI) causes the Peak-to-Average Power Ratio (PAPR) at the receiver to increase significantly, sometimes exceeding 10 dB. High PAPR requires receivers with a large dynamic range, leading to higher circuit […] Read More >

Leading Researchers:
2025-0007

Peptide Condensate Platform for High-Capacity Delivery of Hydrophobic Active Ingredients

Hydrophobic active ingredients are widely used across cosmetics, food-tech, and pharmaceuticals, yet their formulation remains a key challenge due to poor solubility, limited loading capacity, and complex delivery systems. We present a proprietary peptide-based condensate platform that enables efficient, high-capacity encapsulation of hydrophobic molecules within biocompatible, liquid-like microcompartments. This tunable and scalable technology enhances solubility […] Read More >

Leading Researchers:
2-2018-1209

Genetic Engineering of B Cell Receptors for Antigen-Induced, Evolvable Antibody Secretion

We developed a platform for engineering B cells via targeted integration of antibody sequences into the immunoglobulin heavy chain (IgH) locus, enabling physiological expression as a B cell receptor (BCR) and subsequent antigen-induced secretion. Unlike conventional antibody therapies or ectopic expression systems, this approach preserves key adaptive immune functions including antigen-dependent activation, class-switch recombination (CSR), […] Read More >

2025-0052

A Female-Locust-Inspired Hybrid Soft-Stiff Robotic Digger: Mimetics and Implications for Digging Efficiency

Traditional subterranean propagation whether for utility infrastructure, mining, or environmental monitoring often relies on heavy, energy-intensive machinery that removes soil to create space. These methods are frequently destructive, difficult to scale down for precision applications (like biomedical surgery), and struggle in heterogeneous or granular environments. There is a critical market need for minimally invasive, energy-efficient, […] Read More >

Leading Researchers:
2025-0115

Xeno Free Peptide–Cellulose Bioinks for 3D Bioprinting

Current 3D‑printing bioinks rely heavily on animal‑derived collagen/gelatin or GelMA, with variability, pathogen and immunogenicity concerns, and reliance on UV or chemical crosslinking that can harm cells. There is a growing demand for fully xeno‑free, mechanically tunable bioinks that print complex, load‑bearing constructs without external crosslinkers while maintaining high cell viability. The technology: A fully […] Read More >

Leading Researchers:
2-2021-1666

Developing Cultivated Meat from Pluripotent Stem Cells

The global demand for sustainable, ethical, and safe meat sources has surged in recent years, driven by concerns over environmental impact, animal welfare, and food security. Traditional livestock farming, while historically the primary means of meat production, faces significant challenges including land use, greenhouse gas emissions, resource consumption and public health risks. Advances in stem […] Read More >

Leading Researchers:
5-2021-1546

Source Invariant Machine Learning Platform for Robust Clinical Condition Prediction

Clinical and digital‑health models must integrate data from many heterogeneous and rapidly changing sources (EHR systems, devices, apps), making conventional models fragile when inputs or formats change.​ Maintaining and re‑validating separate models for each data source or version is costly and slow, limiting deployment of AI‑based decision support at scale.​ The technology Autoencoder modules trained […] Read More >

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