Homocysteine fibrillar assemblies display crosstalk with Alzheimer’s disease amyloid polypeptide
High levels of homocysteine (Hcy) are reported as a risk factor for Alzheimer’s disease (AD). Correspondingly, inborn hyperhomocysteinemia is associated with an increased predisposition to the development of dementia in later stages of life. Furthermore, despite the apparent association between protein aggregation and AD, attempts to develop a therapy that targets explicitly this process have […] Read More >
Development of Alzheimer Disease therapy based on counteracting the pathological effects of ApoE4
Alzheimer’s disease (AD) is the most common cause of dementia and is the outcome of progressive brain cells death. Due to the disorder’s heterogeneity and in view of the variety of pathological mechanisms inducing the disease we have undertaken an innovative – science based (Animal model) approach, which is presented here. Our unique approach […] Read More >
It is clear that DNA can be used as a storage medium, each nucleotide carrying two information bits, which can store vast amounts of data for very long periods of time and with high reliability; as overtime, humans remain human just as cats remain cats. However, it is also clear that it is a very […] Read More >
Automatic Music Transcription in The Wild using Unaligned Supervision
We have developed a novel system that enables automatic transcription of real musical performances. The system detects in unmatched high accuracy which notes were played, at what time, and by which instrument. In other words, the system can parse the musical content from a recording with high precision in timing and instrumentation. The prediction of […] Read More >
We present a method for the generation of THz pulses with tailored temporal shape from nonlinear metasurfaces. The method is based on single-cycle THz emission by the metasurface inclusions. We show that the spatial amplitude and phase structure of the nonlinear response is mapped to the temporal shape of pulses emitted at certain angles. We […] Read More >
The piezoelectric effect, the conversion of mechanical energy to electrical energy can serve as the basictechnology for many applications such as energy harvesting sensing and actuating. Currently, the fieldof piezoelectric materials is dominate by lead-based ceramic materials such as lead zirconate titanate(PZT). However, lead is toxic and brittle, emerging the need for alternative lead free, […] Read More >
FABRICATION OF ELECTRODES WITH ULTRA-SHORT CHANNEL LENGTH
Nanofabrication represents one of the most important features of modern electronics, optoelectronics, photonics and information technologies. However, the ability to fabricate nanoscale (sub-20 nm) devices, requires the introduction of unconventional techniques for material patterning, which is cumbersome, expensive, time consuming, typically available mainly to big industrial companies or to specific research centers, hence, not reachable […] Read More >
Microfluidic Flow-meter and Sensor for Drug Delivery Applications
The current structure of medical pumps does not allow real-time measurement of different parameters of drug delivery in general and low flow rates (μL/min) in particular. The current structure wherein only indirect measurements are performed (commonly pressure) makes it difficult to detect failures (e.g. air bubbles, occlusion, infiltration) in real-time on the one hand and […] Read More >
Advanced Sensitivity in Point-of-Care Diagnostics: Electrokinetic Preconcentration Technology
As is evident from the lateral-flow-assay (LFA) that became so popular with detection of Corona virus, there is an urgent need to increase the sensitivity of detection of both point-of-care (POC) and self-testing (for example, used by individuals at home) devices. Lateral flow kits result in relatively low detection limit as only a small fraction […] Read More >
Optimal retrieval in puzzle-based storage (PBS) systems using automated mobile robots (AMR)
Puzzle-based systems (PBS), store unit loads in very high density, without consuming space for transport aisles. In such systems, each load is stored on a moving device (conveyor module or transport vehicle), making these systems very expensive to build and maintain. We propose a new type of PBS system where loads are moved by a […] Read More >
Prof. Abelson Avigdor is a marine ecologist, dedicated to the promotion of marine conservation and restoration, through research and planning, and working as a consultant for governmental and non-governmental organizations worldwide (pro bono). His major concern is how to halt the rapid degradation of marine ecosystems and their essential services to humans. Likewise, working on […] Read More >
Research in my Laboratory of Bioinspired Materials is focused on mimicking self-assembly processes that occur in nature, including biomineralization and the organization of short peptides and amino acids into ordered nanostructures. We are a material science laboratory with emphasize on organic chemistry and medical-biological applications. The group is developing new organic materials that are used […] Read More >
Prof. Afek Yehuda
My research interests span the range from distributed systems to tightly coupled multiprocessors. In particular, I am interested in the theoretical study of asynchrony and its effects in systems (both shared memory and message passing based), in concurrent programming (concurrent data structures and transactional memory), and in networking (network security, protecting against denial of service […] Read More >
Dr. Afriat Herskovits Anat
Our lab is focused on understanding the interactions between the human bacterial pathogen Listeria monocytogenes and mammalian cells, specifically, macrophage cells. We explore different strategies of L. monocytogenes that allow it to infect and replicate efficiently within mammalian cells, evade recognition by the innate immune system and manipulate host cellular pathways. We combine computational, biochemical and genetic approaches to […] Read More >
My lab is currently researching these topics: A novel bacterial route for the synthesis of glutathione: A multifunctional fused protein (GshF) integrates the two primary catalytic activities. Development of new selective and essential targets for antibiotics, and their use in specific drug discovery programs. The Ribonucleotide reductase system of Staphylococcus aureus and Streptomyces coelicolor. Studies on control of […] Read More >
Research Projects Innovative Materials Discovery Our cutting-edge computational hardware and efficient software enable us to identify and predict new materials before synthesis. This groundbreaking approach has led to the discovery of 11 novel semiconductor materials, with international patents acquired by Panasonic Corporation. Machine Learning for Targeted Discovery While we excel in materials discovery, our research […] Read More >
Service Laboratory for Biomass Separation and Processing
Prof. Alexander Golberg’s laboratory is equipped with advanced facilities designed to support a wide range of biomass separation and processing needs. Our comprehensive suite of equipment and expertise enables us to offer high-quality services to academic researchers, industry partners, and governmental agencies involved in biomass conversion, waste management, and biofuel production. Equipment and Capabilities 1. […] Read More >
The lab focuses on uncovering the dynamics and cellular processing governing neurovascular coupling under healthy and pathological conditions Specific Research interests/topics: • Neurovascular coupling • Multiphoton imaging • Ischemia, gray matter vascular occlusions • Microglia and neuro-immune responses Research methods: • In vivo imaging methods: two-photon microscopy, wide-field calcium imaging, MRI. • Novel spatial decision […] Read More >
We focus on understanding early developmental cell fate decisions and patterning using embryonic stem cell-based in-vitro models of early development. Read More >
The Rosenfeld Lab- Nanoengineering for Biomedicine
Our lab integrates a wide array of disciplines, including bioengineering, cell biology and materials science, towards development of peripheral organs modulation approaches. Our goal is to advance the fundamental understanding and therapeutic approaches for treating organ dysfunction and connecting it to the nervous system. We develop novel clinically translatable nanomaterials and nanocomposites for spatially and […] Read More >
In the broadest terms, we try to understand the psychological processes of knowledge construction; i.e., the mechanisms whereby humans understand and predict their reality. We are interested in the construction of knowledge about the self (e.g., the self-concept) and the social world (e.g., ideology); one’s personal past (e.g., autobiographical memory) and about the future of […] Read More >
The activity of our lab is concentrated on the spatial behavior of people in the urban environment. We investigate how spatial behaviors, such as movement/mobility, wayfinding and functional-social activities, relate to the characteristics and structure of the urban environment. For that aim, we use spatial, topological and visual analytic tools as well as geographic Information […] Read More >
Based on high-resolution GIS and big data on human and institutions’ spatial behavior, we model the complex geographic system as collectives of decision-makers who define system’s spatio-temporal dynamics and evolve themselves. Smartcard and Cellular data analysis Based on the Smartcards and Cellular data we estimate the demand for public transport and compare it to the […] Read More >
Image Processing and Analysis and in Computational Vision.
Research interests: Applications of Differential Geometry ideas and techniques in Image Processing and Analysis and in Computational Vision. My former research studies were devoted to Conformal Field Theories and Integrable Models in relation to String Theory and to Statistical Mechanics. The Beltrmai framework A differential geometric framework for image processing and analysis. Different objects of […] Read More >
In Dr. Berinskii’s group, we use continuous and discrete methods to investigate the mechanical properties of materials and structures. Continuum representation of material is widely accepted in the mechanics of solids. However, at the micro and nanoscale, the microstructure plays a crucial role and cannot be ignored. At these scales, the models representing a discrete […] Read More >
