Medical Ultrasound Technologies for Diagnostics, Monitoring, and Therapy for Clinically Relevant Problems

The Ilovitsh lab at Tel-Aviv University- We develop noninvasive medical ultrasound technologies for diagnostics, monitoring, and therapy for clinically relevant problems. Our research is highly multidisciplinary, combining engineering, physics, biology, chemistry and medicine. We utilize the unique ability of sound waves to penetrate deep into the body, in some cases even through an intact skull, and couple it with gas-bubbles. These bubbles are efficient theranostic probes that can be used for simultaneous imaging and controlled therapy at a targeted site. We develop enhanced ultrasound-mediated gene delivery methods, noninvasive ultrasound surgery, and safe and precise blood brain barrier opening for brain therapy. In parallel, we are developing optically-inspired ultrasonic techniques for overcoming current limitations in ultrasound imaging. Current interests include 3D ultrasound, super-resolution, image processing and machine learning.

IMAGING

  • Beam shaping ultrasound imaging
  • Ultrasound speed of sound imaging
  • Contrast harmonic imaging
  • Ultrasound localization microscopy

THERAPY

  • Brain therapy
  • BBB opening with FUS+MB for delivery of theraputic mRNA-IL7-LNPs in GBM
  • Low energy ultrasound surgery using nanodroplet-mediated histotripsy
  • Nanobubbles and ultrasound as a platform for enhanced delivery to brain tumors
  • Passive Acoustic Mapping
  • Sonoporarion for drug and gene delivery
  • Tumor ablation

For more information:
Dr. Tali Ilovitsh
Office: Broadcom Building, room 210
Lab: Broadcom Building, room 216
Tel-Aviv University, Tel Aviv, 69978, Israel
+972-73-3804716
ilovitsh@tauex.tau.ac.ilB

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