The lab focuses on uncovering the dynamics and cellular processing governing neurovascular coupling under healthy and pathological conditions

Specific Research interests/topics:
• Neurovascular coupling
• Multiphoton imaging
• Ischemia, gray matter vascular occlusions
• Microglia and neuro-immune responses

Research methods:
• In vivo imaging methods: two-photon microscopy, wide-field calcium imaging, MRI.
• Novel spatial decision making automated task
• Whole-brain cleared tissue imaging.

Main projects in the lab include:
1. Decoding the neurovascular transform function
2. Determining the role of lipid droplets in stroke outcome
3. Spatial decision making
4. Volumetric multi-photon imaging.

Lab Facilities and capabilities:
The PBlab has extensive experience performing in vivo brain imaging, including measuring neuronal dynamics, blood flow, microglia-tumor interactions and other.
We provide a unique approach for longitudinal pharmaco-kinetics, directly measuring particle transfer across brain compartments, from the blood stream to the parenchyma on the same animals over hours or dyas.

Available Research Services:
1. In vivo brain imaging
2. In vivo pharmacokinetics
3. In vivo Blood-brain-barrier permeability assays

Potential industries:

1. Pharma
2. Biotech

Website: https://pblab.tau.ac.il
Email: pb@tauex.tau.ac.il