The Lab for Protein Engineering and Drug Discovery

Modulation of protein-protein interactions is a key for a broad range of biotechnological applications. In our lab, we are developing unique approaches from small molecules, peptides, and optimized proteins to inhibit specific interactions. We are utilizing advanced computational, biophysical and cellular biology techniques. 

Specific Research interests: 
• Engineering of unique Immune modulators 
• Engineering of optimized proteins for biomedical applications

Research methods: 
• Recombinant proteins expression and purification
• Biophysical tools
• Protein engineering
• Computational chemistry

Main projects in the lab include:
1. Harnessing protein interactions for enhanced collagen production
2. Engineering of bacterial pathways for enhanced production of essential amino acids
3. Enzymes for non-invasive dental medicine
4. Optimized peptides and low molecular weight proteins as immunosuppressants

Lab Facilities and capabilities:
• Protein expression and purification
• Engineering of high-affinity peptide/protein binders
• Biophysical protein-protein binding characterization
• Evaluation of enzymatic reactions
• Broad range of plate-reader based applications
• Cellular biology

Potential industries:
1. Pharma
2. Biotech
3. Agtech
4. Foodtech

Contact:
Email: mayyanga@tauex.tau.ac.il
Website: https://maayaangaal.wixsite.co…

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