The Neuropsychiatry & Neuromodulation Lab

Research Teams:

Neuropsychiatry & Neuromodulation
Research Goal- To portray and probe human mental processing related to subjective emotional experience, by identifying their underlying brain activity, connectivity and complex dynamics. This over-arching goal is pursued through research in four themes:

Advanced Brain Imaging:
Research Goal- To characterize the brain tissue and the cerebral-vascular system using multi-parametric advanced MR methods, for data acquisition and analysis, with the goal of improving identification, diagnosis and therapy response assessment for various brain pathologies.

Brain Informatics & Imaging
Research Goal- My research focuses on the use of advanced computer vision methods, based on imaging data (with emphasis on MRI), and combined with additional clinical data to improve diagnosis and follow-up of patients with brain pathologies.
In these studies, emphasis is placed on the interface with the clinic, from the stage of the study design and results validation, to the integration of the developed methods in clinical practice, with the aim of providing clinicians computer aided diagnostic tools, to assist in patient assessment.

Neurosurgical Interfaces
Research Objectives- Improve the preservation of high cognitive and affective functions following brain surgery by applying a personally tailored approach.
Develop novel neurosurgical interventions providing treatment for neuropsychiatric diseases. 
Both basic and translational research is performed using advanced imaging methods (structural and functional) along with neuropsychological tools in the neurosurgical context.

Consciousness & Psychopharmacology
Research Goal- Our research goal is to advance the understanding of brain processes underlying consciousness and the subjective human experience.  To that aim we probe brain activity by using an array of advanced functional neuroimaging techniques during resting state and in response to different stimuli, as well as following modulation of brain activity by applying behavioral and pharmacological interventions as well as brain-computer interfaces.

Cognitive Resource and Plasticity
Research Goal- The team focuses on the study of the neural activity underlying complex naturalistic events. Our research involves functional and structural brain imaging, neuropsychological assessments and physiological measurements. We apply our paradigms to neuro-psychiatric disorders (e.g. mild cognitive impairment (MCI), schizophrenia, etc.), in order to better understand various pathological conditions.
To study factors of vulnerability in a causal manner we apply either a prospective imaging approach, or compare groups of affected and unaffected individuals under similar conditions (e.g. older adults and participants with MCI, patients with schizophrenia and their unaffected siblings). While applying multi-modal paradigms, we are focused on developing methods for the identification of “functional neuromarkers” for these diseases.

Immersive brain-computer interfaces
Research Goal- Basic research and development of methods involving audiovisual brain computer interfaces, virtual reality, and augmented reality for psychiatry, rehabilitation, and enhancement. The lab focuses on translational research, which integrates these technologies in the treating psychopathologies such as depression, anxiety, and addiction, cognitive rehabilitation, and learning.
The work in the lab is based on neuroimaging methods including encephalography (EEG), functional magnetic resonance imaging (fMRI) and Functional near-infrared spectroscopy (fNIRS).

For more information:
Email: thendler@tauex.tau.ac.il
Fax: 03-6973080
Website: https://www.cbf-tlv.com/
Office: Sharett – Educational Sciences, 151א

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