UNMET NEED

As biological models continue to evolve from traditional 2D cultures to complex 3D tissues, organoids, and bioprinted constructs, there is a growing need for sensing technologies capable of monitoring functionality within these physiologically relevant systems. Current sensing platforms, including conventional MEA and TEER systems, are largely limited to two-dimensional measurements.

OUR SOLUTION

Researchers at Tel Aviv University have developed a customizable 3D sensing platform that enables monitoring of advanced in vitro brain and neurovascular models. The platform combines electrophysiological recording and barrier-function measurements within a single system and can be adapted to various organoid, neurovascular, and bioprinted tissue configurations.

APPLICATIONS 

• Brain organoid research
• Neurovascular Unit (NVU) and Blood-Brain Barrier (BBB) models
• Drug discovery and neurotoxicity testing
• Tissue engineering and bioprinting platforms
• Advanced in vitro disease models

STATUS
Proof-of-concept demonstrated

INTELLECTUAL PROPERTY
PCT Patent Application WO2024/009309

Availability: Available for licensing and commercial development