11-2021-1544

Anti-Oxidation Agent to be Incorporated Into Cosmetics Leading to More Stable and Longer Shelf-Life Products

Oxidation is the reaction of Oxygen with a wide array of reactants. In cosmetics, product oxidation leads to spoilage of ingredients used in the manufacturing products, the inactivation of oxygen-sensitive enzymes, shortening of product shelf-life, and discolorations of end-product.
Self-assembling peptide-based hydrogels are simple hydrogels that can be combined with a wide variety of ingredients and are able to encage O2 and significantly limit its diffusion and penetration.

APPLICATIONS
• The hydrogels nanofibers can be incorporated in topical cosmetics to protect the skin
• Incorporation of the hydrogel into cosmetics may prevent discoloration caused by oxidation
• Prolong shelf-life of manufacturing reagents or end-products

STATUS
• The peptide hydrogels limit the diffusion of Osignificantly better than other hydrogels.
• Binding is specific to O2.
• Also works in liquid suspension with a low peptide concentration

INTELLECTUAL PROPERTY
US Provisional Patent

REFERENCES
Ben-Zvi, O., Grinberg, I., Orr, A. A., Noy, D., Tamamis, P., Yacoby, I., & Adler-Abramovich, L. (2021). Protection of Oxygen-Sensitive Enzymes by Peptide Hydrogel. ACS Nano, 15(4), 6530–6539. https://doi.org/10.1021/acsnan…

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