11-2021-1528

Jellyfish׳ Collagen-Based Smart Wound Dressing with Antibacterial Properties

Collagen-based dressing in wounds greatly benefits the healing process. Unfortunately, most collagen is extracted from bovine tissues, which bears a significant risk of transmitting various biological contaminations. Moreover, the collagen extraction process from bovine tissue involves time and cost-consuming steps, reducing the total collagen yield and increasing the overall cost of goods. In addition, the incorporation of silver nanoparticles into wound dressing is known to have a robust antibacterial effect and assist with quicker and healthier wound healing.
‘Smart Wound Dressing’ (SWD) is a collagen-based dressing with incorporated silver nanoparticles derived from Jellyfish with a potent wound healing effect compared to the existing competition 
SWD incorporates other biomaterials with robust therapeutic effects, and its production is based on novel and patented nanotechnology.

ADVANTAGES
• Modular production of a variety of wound types 
• The manufacturing process is easily upscaled and more cost-efficient than existing alternatives.
• The product is biocompatible with various tissues.
• The raw material (jellyfish) is an unwanted commodity and should be supplied at little or no cost.

APPLICATIONS
• SWD displays a significant advantage over other silver nanoparticle-containing dressings in the market
• Excessive collagen produced in the process can be sold and used for additional applications (cosmetics, scaffold for tissue engineering, etc.)

STATUS
Successful in-vivo experiments in porcine 

INTELLECTUAL PROPERTY
Granted EU Patent

REFERENCES
Nudelman, R., Alhmoud, H., Delalat, B., Fleicher, S., Fine, E., Guliakhmedova, T., Elnathan, R., Nyska, A., Voelcker, N. H., Gozin, M., & Richter, S. (2019). Jellyfish-Based Smart Wound Dressing Devices Containing In Situ Synthesized Antibacterial Nanoparticles. Advanced Functional Materials, 29(38), 1–11. https://doi.org/10.1002/adfm.2…

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