2025-0098

Ultrasound-Based Monitoring of Hemostatic Gelation

This novel, noninvasive ultrasound-based method enables real-time monitoring of gelation in hemostatic materials by tracking changes in the speed of sound (SoS) within the material. The system uses advanced image processing (dense optical flow) and acoustic modeling to detect viscosity changes during the transition from liquid to gel.
Unmet Need
Current wound care solutions lack tools for real-time, quantitative assessment of hemostatic material performance. Existing methods are manual, invasive, or unreliable in field or surgical conditions.

Key Advantages
• Real-time, noninvasive gelation tracking
• Quantitative and reproducible
• Easily integrated with standard ultrasound systems
• Applicable in both clinical and emergency settings

Applications
• Surgical and trauma care
• Military field medicine
• Development and testing of bioadhesives and gels

Development Status
Validated in gelatin models; aligns with mechanical gelation benchmarks.
Ready for adaptation to clinical-grade hemostatic materials.

 

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